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Clinical Trials

Is there a clinical trial that's right for you?

Now bringing the benefits of an expanded, enhanced clinical trials program to the local community.

We have worked to make clinical research studies a vital component of our healthcare delivery capabilities. Now, through our Office of Clinical Trials, all the residents in our 16-county service area can potentially benefit from the search for new treatments, new medications, and new procedures which these trials make possible.

The Office of Clinical Trials (OCT) oversees research projects using UHS Hospitals facilities and resources. We work with pharmaceutical and other medical companies to conduct clinical research studies. With over 16 years of experience conducting complex clinical research and enrolling patients in the study of investigational medication and devices, OCT follows careful processes to protect the best interest of our research patients, while at the same time adhering to federal and other regulatory guidelines for compliance.

We are committed to maintain a high standard of commitment to clinical research, as reflected in our mission statement.

Existing Clinical Trials

Cardiac Studies


This study determines the safety, tolerability, pharmokinetics and efficacy on intravenous infusion of study drug to patients with new onset Paroxysmal or Persistent Atrial Fibrillation.
Sponsor: Otsuka Pharmaceuticals
Principal Investigator: Dr. Hisham Kashou


This study is to collect real world data on important outcome events of antithrombotic treatments for prevention of stroke in patients with non-valvular Atrial Fibrillation.
Sponsor: Boehringer Ingelheim
Principal Investigator: Dr. Hisham Kashou

Surgical Studies


This study compares the safety and efficacy of the Coloplast Exair Prolapse Repair System (mesh) for treatment of pelvic organ prolapse compared to traditional native tissue repair.
Sponsor: Coloplast
Principal Investigator: Dr. Barbara Wiseman

Pregnancy Studies


This study collects bio-fluid samples from Pregnant Women for the evaluation of biomarkers for preeclampsia.
Sponsor: Discovery Life Sciences
Principal Investigator: Dr. Iskandar Kassis

Post Discharge Studies


This study evaluates medically ill patients assessment of Rivaroxaban versus placebo in reducing post-discharge venous thrombo-embolism risk.
Sponsor: Janssen Research and Development
Principal Investigators: Dr. Nazif Chowdhury

Neurological Studies

Respect (ESUS)

This study compares the safety and efficacy of the oral Thrombin Inhibitor dabigatran etexilate versus aspirin in patients with Embolic Stroke of Undertermined Source.
Sponsor: Boehringer Ingelheim
Principal Investigator: Dr. Aamir Rasheed


This study is to determine therapeutic benefit of Intensive Systolic Blood Pressure treatment (SBP < 140 mmHg) compared to Standard Systolic Blood Pressure (SBP < 180 mmHg) in reducing proportion of patients with death and disability (mRS of 4-6) at 90 days post randomization among subjects with Intracerebral Hemorrhage with treatment instituted within 4.5 hours of symptom onset.
Sponsor: National Institute of Health
Principal Investigator: Dr. Yahia Lodi

Pneumonia Studies

Bayer/Inhaled Amikacin

This study evaluates the safety and efficacy of aerosolized amikacin as adjunctive therapy in intubated and mechanically ventilated patients with gram negative pneumonia.
Sponsor: Bayer Healthcare
Principal Investigator: Dr. Michael Chisdak


This study evaluates the safety and efficacy of IV to Oral Solithromycin compared to IV to oral Moxifloxacin in treatment of adult patients with Community Acuired Bacterial Pneumonia. 
Sponsor – Cempra
Principal Investigator – Dr. Nazif Chowdhury

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